Rose was born in the American colonies. She and Boston were parents to nine children: Lydia, Boston Jr., Thomas, Thomas Boston, Jemima, Liverpool, Richard, Rebeckah, and Bristow. They resided on Charter Oak Avenue in West Hartford before moving to Rocky Hill, CT. The couple was freed in 1774, but their nine children would stay enslaved for 11 more years until finally being granted freedom due to the death of their enslaver.